Prana Biotechnology (ASX:PBT / NASDAQ:PRAN), a leading global developer of first-in-class treatments for neurodegenerative disease, has today provided an update on three clinical trials testing its proprietary drug, PBT2, in Alzheimer’s and Huntington’s diseases.

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Principal Investigator, Dr James Duce from The University of Leeds, UK, will collaborate with Professor David Finkelstein of The Florey Institute of Neuroscience and Mental Health (FINMH) in Australia and Associate Professor Robert Cherny of FINMH and Prana’s Head of Research on the Study.

Prana Biotechnology today announced that it has received approval from the United States Food and Drug Administration (FDA) to start recruiting patients for the company's first clinical trial using PBT2 in patients with Huntington’s Disease (HD).

Prana Biotechnology today commented on three recent high profile scientific journal articles that the company believes provide support for Prana’s therapeutic strategy for treating neurodegenerative disease.

Prana Biotechnology today announced that the first patient has been dosed in the “IMAGINE Trial” - 12 month Phase II Imaging trial testing PBT2, the Company’s drug in development for Alzheimer’s Disease.

Prana Biotechnology today announced the publication in the journal PLoS ONE, of an article that strongly endorses PBT2’s potential to treat Alzheimer’s Disease. The paper, entitled “The Zinc Dyshomeostasis Hypothesis of Alzheimer’s Disease”1 presents an integrated explanation of the major pathological features of Alzheimer’s Disease, based upon a combination of new experimental data and mathematical modeling.

Prana Biotechnology today announced that the first patient has been dosed in the “Reach2HD Trial” – a 6 month Phase IIa clinical trial testing PBT2, the Company’s drug in development for Huntington disease. Reach2HD, a double blind placebo controlled study, is enrolling 100 patients with early to mid-stage Huntington Disease. The Principal Investigator on the study is Dr. Ray Dorsey of Johns Hopkins University.

Prana Biotechnology today commented on the publication of new data of relevance to the current clinical trial, testing Prana’s PBT2 as a treatment for Huntington disease.

Prana Biotechnology today announced that Executive Chairman, Geoffrey Kempler is scheduled to present a corporate update at upcoming healthcare conferences in Australia and the US.