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Category: Investor Announcement

PLoS ONE Journal Publishes Mechanistic Model of Alzheimer’s Disease Endorsing Prana’s PBT2

Prana Biotechnology today announced the publication in the journal PLoS ONE, of an article that strongly endorses PBT2’s potential to treat Alzheimer’s Disease. The paper, entitled “The Zinc Dyshomeostasis Hypothesis of Alzheimer’s Disease”1 presents an integrated explanation of the major pathological features of Alzheimer’s Disease, based upon a combination of new experimental data and mathematical modeling.

Prana Enrolls First Patient in the “Reach2HD” Phase II Huntington Disease Trial

Prana Biotechnology today announced that the first patient has been dosed in the “Reach2HD Trial” – a 6 month Phase IIa clinical trial testing PBT2, the Company’s drug in development for Huntington disease. Reach2HD, a double blind placebo controlled study, is enrolling 100 patients with early to mid-stage Huntington Disease. The Principal Investigator on the study is Dr. Ray Dorsey of Johns Hopkins University.

Prana’s PBT2 presented at the Huntington’s Disease Society of America National Convention: Prana’s ‘Reach2HD’ Phase II trial on track

Prana Biotechnology today announced that an update on Prana’s Phase 2 clinical trial in Huntington disease (HD) was presented at the HDSA annual National Convention held in Las Vegas, Nevada over the weekend. Professor Ira Shoulson, Professor of Neurology, Pharmacology and Human Science and Director, Program for Regulatory Science & Medicine at Georgetown University spoke to the ‘Reach2HD’ trial objectives and potential future of PBT2 as a novel therapeutic strategy for the treatment of HD.