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Alterity Therapeutics is developing best-in-class therapies to treat neurodegenerative disease.

The Company was incorporated in 1997 in Melbourne, Australia and listed on the Australian Securities Exchange in 2000 and NASDAQ in 2002 as Prana Biotechnology. It changed its name by Shareholder Approval on 5th April 2019.

The company operates under the tickers ASX: ATH and NASDAQ: ATHE.


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Investment Highlights

  • Well-funded clinical stage drug development company following up to $44M strategic investment led by Life Biosciences LLC allowing accelerated and focused clinical development.
  • Strong and highly experienced board and management team with significant R&D and commercialisation experience including 3 drug approvals by US FDA.
  • PBT434 is a novel drug candidate targeting key proteins implicated in neurodegeneration of Parkinson’s disease and atypical parkinsonism.
  • PBT434 is completing its Phase 1 clinical trial program.
  • First therapeutic target selected – Multiple System Atrophy (MSA), a form of atypical parkinsonism, is a devastating disease with no approved treatments.
  • FDA Orphan Drug designation for PBT434 for the treatment of MSA received.
  • Significant market potential for MSA alone – estimated peak sales of US$750M.

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Highlights: Completion of Phase 1 Clinical Trial; PBT434 found to be safe and well-tolerated; clinically tested doses achieve concentrations

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